Protein name:
Vacuolar protein sorting-associated protein 29 ;
Alternative:
Vesicle protein sorting 29 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN (By similarity). Component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2.
Function:
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
Subcellular Location:
Cytoplasm
Membrane
Peripheral membrane protein
Endosome membrane
Peripheral membrane protein
Protein Attributes:
50:
MLVLVLGDLH | IPHRCNSLPA | KFKKLLVPGK | IQHILCTGNL | CTKESYDYLK |
100:
TLAGDVHIVR | GDFDENLNYP | EQKVVTVGQF | KIGLIHGHQV | IPWGDMASLA |
150:
LLQRQFDVDI | LISGHTHKFE | AFEHENKFYI | NPGSATGAYN | ALETNIIPSF |
182:
VLMDIQASTV | VTYVYQLIGD | DVKVERIEYK | KS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Mouse
Bovine
ELISA Kit for Mouse Vacuolar protein sorting-associated protein 29
ELISA Kit for Mouse Vacuolar protein sorting-associated protein 29
ELISA Kit for Mouse Vacuolar protein sorting-associated protein 29
ELISA Kit for Mouse Vacuolar protein sorting-associated protein 29
ELISA Kit for Mouse Vacuolar protein sorting-associated protein 29
CLIA Kit for Mouse Vacuolar protein sorting-associated protein 29
CLIA Kit for Mouse Vacuolar protein sorting-associated protein 29
CLIA Kit for Mouse Vacuolar protein sorting-associated protein 29
CLIA Kit for Mouse Vacuolar protein sorting-associated protein 29
CLIA Kit for Mouse Vacuolar protein sorting-associated protein 29
Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Polyclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Monoclonal Antibody for Mouse Vacuolar protein sorting-associated protein 29
Protein for Mouse Vacuolar protein sorting-associated protein 29
Protein for Mouse Vacuolar protein sorting-associated protein 29
Protein for Mouse Vacuolar protein sorting-associated protein 29
Protein for Mouse Vacuolar protein sorting-associated protein 29
Protein for Mouse Vacuolar protein sorting-associated protein 29
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface."
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ANKRD27;MUTAGENESIS OF LEU-152
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS;ABSENCE OF CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;SUBUNIT;MUTAGENESIS OF ASN-39; VAL-90 AND ILE-91
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Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Lung .
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Bone marrow .
tissue :
Embryo .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Mammary tumor .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1-14;IDENTIFICATION BY MASS SPECTROMETRY
tissue :
Hippocampus .
7.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;LACK OF PHOSPHATASE ACTIVITY;INTERACTION WITH SNX1
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT